Therapy of Pulmonary Edema

K. Brigham
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引用次数: 2

Abstract

Any rationale for therapy in patients with pulmonary edema depends on the therapeutic endpoint. As discussed earlier in this volume, there are several abnormalities of lung function, in addition to edema (that is, excess fluid in the lungs), that may be major contributors to the hypoxemia, so that if oxygenation is the variable used to assess the effectiveness of therapy, manipulations which reduce the amount of edema may not appear efficacious. It may well be that drugs that may improve airway function or alter functions of the pulmonary vasculature are therapeutic in some conditions even though they do not improve oxygenation or reduce the amount of edema. This article will deal only with therapies aimed at reducing the amount of edema in the lungs or preventing further accumulation of edema fluid. The discussion will present rationales based on what is known about the pathogenesis of pulmonary edema, discussed in the previous articles.
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肺水肿的治疗
对肺水肿患者进行治疗的任何理由都取决于治疗终点。正如本卷前面所讨论的,除了水肿(即肺部液体过多)外,还有几种肺功能异常,这可能是低氧血症的主要原因,因此,如果氧合是用于评估治疗有效性的变量,那么减少水肿量的操作可能看起来并不有效。很可能改善气道功能或改变肺血管功能的药物在某些情况下是治疗性的,即使它们不能改善氧合或减少水肿。本文将只讨论旨在减少肺部水肿量或防止水肿液进一步积聚的治疗方法。本文将根据先前文章中所讨论的关于肺水肿发病机制的已知知识提出基本原理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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Future Directions for Clinical Medicine Primary (High Permeability) Pulmonary Edema Pulmonary Vascular Reactivity in Primary Pulmonary Edema Therapy of Pulmonary Edema Editor's Perspective
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