IMPACT OF THE SUBLETHAL CONCENTRATIONS OF CYPERMETHRIN TOXICITY ON NITROGEN METABOLISM IN FRESH WATER FISH HETEROPNEUSTES FOSSILIS

Abstract

Cypermethrin is a synthetic pyrethroid pesticide (C H Cl NO ) that has shown effective impact of strong pesticidal 22 19 2 3 activity observed in Heteropneustes Fossils, a fresh water fish exposed to sublethal concentrations of cypermethrin in different tissues liver, gill, and muscle for 4 and 7 seven days. The enzyme activity of Glutamate Dehydrogenase (GDH) was increased all the tissues especially in liver and gill. Significant change might be attributed to tissue change under toxic stress in Heteropneustes fossils. The increased levels of Urea and Ammonia also noticed indicate remarkably the role as biomarkers of cypermethrin toxicity. And the raise in Ammonia as well as urea levels indicates the concentration and tissue dependent which in turn helps to assess the impact of synthetic pyrethroids on the fish. The changes in Ammonia and Urea levels is often be reflected in nitrogen metabolism and interdependent biochemical reactions.