Rett Syndrome

Abstract

Rett syndrome is a rare developmental disorder which affects the brain development and the symptoms grows as the age progresses. It is first seen at the age of 6-18 months and predominantly seen in females; cases with male children are limited. 95% of the Rett syndrome cases are known to be due to mutation in MeCP2 genes present in the X chromosome. Approximately 3, 50,000 cases have been reported worldwide and the cases are growing. In India, 6 cases of Rett syndrome were encountered in the year 1992 and 1993 but was misdiagnosed; correctly reported in the year 1994. The cure is unknown for the syndrome but multidisciplinary approach helps in addressing the symptoms effectively.