Artem Goncharov, Hyou-Arm Joung, Rajesh Ghosh, Gyeo-Re Han, Zachary S. Ballard, Quinn Maloney, Alexandra Bell, Chew Tin Zar Aung, O. Garner, D. Di Carlo, Aydogan Ozcan
{"title":"Fluorescence-based multiplexed point-of-care sensor using deep learning","authors":"Artem Goncharov, Hyou-Arm Joung, Rajesh Ghosh, Gyeo-Re Han, Zachary S. Ballard, Quinn Maloney, Alexandra Bell, Chew Tin Zar Aung, O. Garner, D. Di Carlo, Aydogan Ozcan","doi":"10.1364/boda.2023.dtu3a.7","DOIUrl":null,"url":null,"abstract":"We present a multiplexed paper-based point-of-care sensor processed by a hand-held fluorescence reader and neural networks that quantify three cardiovascular disease biomarkers from human serum samples, achieving a limit-of-detection of ≤0.52 ng/mL for each biomarker.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1364/boda.2023.dtu3a.7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
We present a multiplexed paper-based point-of-care sensor processed by a hand-held fluorescence reader and neural networks that quantify three cardiovascular disease biomarkers from human serum samples, achieving a limit-of-detection of ≤0.52 ng/mL for each biomarker.