Model-based optimal control method for cancer treatment using model predictive control and robust fixed point method

Abstract

Cancerous diseases are being responsible for the death of many around the globe. Treating these illnesses pose a significant challenge to the medical professionals. While conventional methods, chemotherapy or radiotherapy for example, provide a remedy to the issue their side effects are not negligible. In the past few decades new methods have emerged, which could hinder the strength of the side effects and most remarkably, anti-angiogenic therapy can make a notable difference in every day cancer treatment. While the technique has many advantages the cost of treatments are often expensive due to the non-personalized administration medical protocols. In this paper a model based solution is provided which aims to lower the medical expenses during the treatment by creating personalized administration plans with the help of control engineering.