Metabolic pathway interface to molecular biology databases

Barry Zeeberg, Kevin Watanabe, S. Goto, R. Overbeek, L. Kerschberg, George Michaels
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引用次数: 0

Abstract

We present results of providing database support to biomedicine via federation of SDB Cooperation/Integration based upon the KEGG GUI for molecular biology. The federation provides a common link to three molecular biology databases. The added value of the federation is freedom from consulting multiple references to ascertain the full set of enzymatic reactions in a metabolic pathway, and the option of selecting multiple queries to submit to the federated SDBs. Each of the SDBs is extensive, but incomplete. The union of the SDBs, implemented transparently by the federation, is more complete. Each SDB provides a different approach to the options available for data presentation and a different set of Web server tools for data analysis. Thus, an important part of the added value of the federation is the cross-fertilization available in the union of the molecular biological content, the presentation of data, and the tools available for analysis.
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代谢途径接口到分子生物学数据库
本文介绍了基于分子生物学KEGG GUI的SDB合作/集成联盟为生物医学提供数据库支持的结果。该联盟提供了三个分子生物学数据库的公共链接。联合的附加价值在于,不必咨询多个参考来确定代谢途径中的全部酶促反应,并且可以选择向联合sdb提交多个查询。每个sdb都很广泛,但不完整。由联盟透明地实现的sdb联盟更加完整。每个SDB为数据表示提供了不同的方法,并为数据分析提供了一组不同的Web服务器工具。因此,联盟附加值的一个重要部分是在分子生物学内容、数据的呈现和可用的分析工具的联合中提供的交叉受精。
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