Three dimensional modeling and analysis of Haversian systems in compact bone tissue

Abstract

This study provides a qualitative as well as quantitative characterization of the geometry and architecture of the Haversian systems at a microscopic level. A three dimensional computer model was created with serial sections of equine bone. From the reconstruction, quantitative calculations were made, including porosity, surface areas, cross sectional areas, and cross sectional shapes. Also the porosity due to Volkmann canals was estimated. Other more qualitative calculations included the nature of branching, termination and general osteon movement. Any change in the specimen size or shape during the entire processing was carefully documented and corrected for where possible. One of the goals of the research was to assess and evaluate the procedures developed and identify was to further improve accuracy. With a computerized three dimensional image of the bone microstructure, detailed calculations can be made and insight gained more accurately than with two dimensional models or past three dimensional models.