Age maculodystrophia: the hypothesis of etiopathogenesis

Abstract

Age-related macular dystrophy (AMD) is one of the main causes of vision loss in old age. The etiopathogenesis of AMD has not been fully elucidated, therefore there is no radical treatment of AMD. The proposed hypothesis is that the trigger of AMD may be a genetically determined weakness of accommodation (related to an excessively small distance "ciliary body - lens equator"). It is necessary to carry out objective accomodometry, OCT diagnostics of the distance "ciliary body - lens equator" in older people with healthy eyes and with ophthalmopathology (including AMD). If the hypothesis is confirmed, it is proposed to: a) surgically expand the ring of the ciliary body; b) to form a simple direct myopic astigmatism of up to 1.5 diopters on an artificial eye with AMD (by calculating the optical power of the IOL or modeling the corneal surface with a femtosecond laser).