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Effect of gestational diabetes on the eye: a mini review 妊娠糖尿病对眼睛的影响:微型综述
Pub Date : 2024-07-19 DOI: 10.15406/aovs.2024.14.00465
Pragati Garg, Parul Sinha
Gestational diabetes mellitus (GDM) is a condition characterized by glucose intolerance that is first recognized during pregnancy. This condition affects a significant number of pregnancies worldwide, with an estimated prevalence ranging from 1% to 14% depending on the population and diagnostic criteria used.1,2 GDM accounts for 90% of diabetes mellitus cases in pregnancy, while pre-existing type 2 diabetes accounts for 8% of such cases.2 While gestational diabetes often resolves after childbirth, it can have profound short- and long-term implications for both the mother and the baby. One of the critical areas of concern is the impact of gestational diabetes on ocular health. This article is based on the effects of gestational diabetes on the eyes, the mechanisms involved, potential complications, and management strategies.
妊娠糖尿病(GDM)是一种以葡萄糖不耐受为特征的疾病,在妊娠期间首次被发现。1,2 GDM 占妊娠期糖尿病病例的 90%,而原有的 2 型糖尿病占此类病例的 8%。2 虽然妊娠期糖尿病通常会在分娩后缓解,但它会对母亲和婴儿产生深远的短期和长期影响。妊娠糖尿病对眼部健康的影响是值得关注的重要领域之一。本文主要介绍妊娠糖尿病对眼睛的影响、相关机制、潜在并发症以及管理策略。
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引用次数: 0
Case report: Retinal alterations in a young patient without comorbidities using injectable testosterone for aesthetic purposes 病例报告:一名无合并症的年轻患者因美容目的使用注射用睾酮而导致视网膜改变
Pub Date : 2024-07-11 DOI: 10.15406/aovs.2024.14.00464
Leticia Aranha Williams de Castro, Rodney Williams de Castro, Amanda Aranha Williams de Castro, Renato Silva Filho
After the significant decision by the Federal Council of Medicine to veto the prescription of testosterone by doctors for aesthetic purposes, the major discussion revolves around the competence of users and other healthcare professionals regarding the monitoring of side effects that impact the patients' quality of life. This is because these individuals may potentially seek other ways to use the anabolic agent. In this case report, we present the case of a young, healthy patient without previous comorbidities, who exhibited significant ophthalmological changes during a routine check-up, consistent with systemic arterial hypertension, which had not been identified during their follow-up consultations with an endocrinologist.
在联邦医学委员会做出否决医生为美容目的开具睾酮处方的重大决定后,主要的讨论围绕着使用者和其他医疗保健专业人员在监测影响患者生活质量的副作用方面的能力展开。这是因为这些人可能会寻求其他方式使用同化制剂。在本病例报告中,我们介绍了一名年轻、健康、无并发症的患者的病例,该患者在一次例行体检中出现了明显的眼部变化,与全身性动脉高血压相一致,但在与内分泌科医生进行随访时并未发现这一症状。
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引用次数: 0
Autoimmune scleritis: A new look at etiopathogenesis and treatment 自身免疫性巩膜炎:发病机制与治疗新视角
Pub Date : 2024-06-11 DOI: 10.15406/aovs.2024.12.00463
Rudkovska Oksana
At present, the etiopathogenesis of autoimmune scleritis is not fully understood, the trigger of the disease is unknown, and treatment is ineffective. The author's hypothesis: the trigger of scleritis may be a weakness of accommodation caused by genetic ("tight" anterior segment of the eye) and epigenetic (chronic stress) factors. In order to restore accommodation, it is proposed to: a). form rounded non-penetrating supraciliary sclerectomies in the upper half of the eyeball (imitation of anterior scleral staphyloma); b).to form simple myopic astigmatism in the cornea up to 1.5 diopters, which gives the maximum amount of pseudo-accommodation (imitation of the effect of peripheral ulcerative keratitis on the refraction of the eye). c). if necessary, to form laser mydriasis. The parameters of operations should be established experimentally. This surgical approach can be applied to the treatment of systemic autoimmune diseases, which are often associated with scleritis and may have a common trigger - poor accommodation.
目前,自身免疫性巩膜炎的发病机制尚不完全清楚,诱发因素不明,治疗效果不佳。笔者假设:巩膜炎的诱因可能是遗传(眼球前段 "过紧")和表观遗传(长期压力)因素导致的调节功能减弱。为了恢复调节能力,建议:a).在眼球上半部进行圆形非穿透性巩膜上切除术(模仿前巩膜葡萄肿);b).在角膜上形成简单的近视散光,最高可达 1.c). 如有必要,进行激光散瞳。手术参数应通过实验确定。这种手术方法可用于治疗全身性自身免疫性疾病,这些疾病通常与巩膜炎有关,并可能有一个共同的诱因--适应不良。
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引用次数: 0
Bilateral anterior capsular phimosis in an 85-year-old female patient after stand-alone cataract extraction with intraocular lens implantation 一名 85 岁女性患者在独立白内障摘除术和眼内晶体植入术后出现双侧前囊膜包茎
Pub Date : 2024-04-10 DOI: 10.15406/aovs.2024.14.00459
Trung Thanh Bui, Ericka J Garcia, Jennifer L Kim
Introduction: Anterior capsular phimosis is a rare complication after cataract extraction with intraocular lens implantation. Patient and clinical findings: An 85-year-old female underwent manual phacoemulsification with toric intraocular lens implantation in the right eye (OD) without any post-operative complications. Approximately 1.5 weeks later, she had the same procedure in the left eye (OS) with similar success. At post-operative week 6 OD and week 4 OS, distance visual acuity without correction was 20/400 OD and hand motion (HM) OS. Anterior segment examination revealed intraocular lens implants with a significant fibrotic anterior capsule in both eyes. Posterior segment examination showed pigmentary macular changes in both eyes that were unchanged from the pre-operative evaluation. Diagnosis, intervention, and outcomes: The patient was diagnosed with bilateral anterior capsular phimosis. She underwent Nd:YAG laser capsulotomy in the left eye, then in the right eye 1 week later. At Nd: YAG laser capsulotomy post-operative day 4 OD and week 2 OS, distance visual acuity without correction was 20/40 OD, OS with best corrected visual acuity 20/30 OD, OS. Conclusions: Anterior capsular phimosis can occur in both eyes sooner than 4 weeks after cataract extraction with intraocular lens implantation in a patient with no risk factors.
简介前囊包皮过长是白内障摘除术并植入人工晶体后的一种罕见并发症。患者和临床发现:一名 85 岁的女性接受了人工乳化手术,并在右眼(OD)植入了散光人工晶体,术后未出现任何并发症。约 1.5 周后,她在左眼(OS)进行了同样的手术,并取得了类似的成功。术后第 6 周(外侧眼)和第 4 周(内侧眼),外侧眼无需矫正的远距离视力为 20/400,内侧眼的手部运动(HM)视力为 20/400。前段检查显示,两只眼睛都有眼内晶状体植入物和明显纤维化的前囊。后段检查显示,双眼黄斑部色素性改变与术前评估结果相同。诊断、干预和结果:患者被诊断为双侧前囊性包茎。她接受了左眼 Nd:YAG 激光囊肿切除术,一周后又接受了右眼囊肿切除术。在 Nd:YAG 激光晶体囊肿切除术后第 4 天(外侧)和第 2 周(内侧),未经矫正的远视力为 20/40(外侧),最佳矫正视力为 20/30(外侧),最佳矫正视力为 20/30(内侧)。结论在白内障摘除术并植入眼内透镜后 4 周内,无风险因素的患者双眼均可发生前囊膜炎。
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引用次数: 0
Comparison between degree of hyperopia and iridocorneal angle, cross-sectional study 远视度数与虹膜角膜角之间的比较,横断面研究
Pub Date : 2024-03-27 DOI: 10.15406/aovs.2024.14.00458
M. P. González, Piero Barrera Arshavin, C. M. Sanguesa, G. E. Torres, J. H. Zech
Objectives: To determine whether there is a correlation between the degree of hyperopia and the presence of a narrow iridocorneal angle (ICA) in the general population. Methods: Cross-sectional study, period December 2022 - June 2023 at the Instituto de la Visión, Chile. Sample size of 177 patients (353 eyes). Hyperopes are classified as mild (less than 3 dioptres), moderate (3 to 6 dioptres), or high (greater than 6 dioptres). The AIC, assessed by gonioscopy (4-mirror gonioscope), according to Shaffer in 4 degrees, dichotomised from 0 to 2 as narrow angle, and 3 to 4 as open. An emmetropic "control" group was maintained, with a range of +/- 0.5 spherical dioptres. Statistical analysis: The chi-square test was used for the association between the two variables. Results: Of the total number of patients, 65% had mild hyperopia (n=229), 13% moderate (n=47), 0.6% high, while 21% corresponded to the "control" group (n=75). Of the total, 41% had narrow angle (n=146) and 59% open (n=207). In the analysis by group, mild hypermetropes showed 46% (n=105) of narrow angles compared to 27% (n=20) of the 'control' group. This difference was statistically significant (p<0.05). When comparing the moderate hyperopia group, which had 40.4% (n=19) of narrow angles, significant differences were observed compared to the 'control group', but not compared to the mild hyperopia group (p=0.2). Conclusion: There is a significant association between hyperopia and narrow AIC measured by gonioscopy, independent of the degree of severity of hyperopia. It is therefore advisable to screen for narrow angles in these patient groups.
研究目的确定普通人群的远视程度与虹膜角膜狭小(ICA)之间是否存在相关性。方法:横断面研究:横断面研究,2022 年 12 月至 2023 年 6 月在智利视觉研究所进行。样本量为 177 名患者(353 只眼睛)。远视分为轻度(小于3度)、中度(3至6度)和高度(大于6度)。根据沙弗尔(Shaffer)的观点,通过球镜(四镜球镜)评估的AIC为4度,0至2度为窄角,3至4度为开角。视力正常 "对照 "组的球面屈光度范围为 +/- 0.5。统计分析:对两个变量之间的关联采用卡方检验。结果在所有患者中,65% 患有轻度远视(人数=229),13% 患有中度远视(人数=47),0.6% 患有高度远视,而 21% 的患者属于 "对照 "组(人数=75)。其中,41%为窄角(146 人),59%为开角(207 人)。按组别进行分析,轻度远视者有46%(n=105)为窄角,而 "对照 "组为27%(n=20)。这一差异具有统计学意义(P<0.05)。中度远视组的窄角比例为 40.4%(n=19),与 "对照组 "相比差异显著,但与轻度远视组相比差异不显著(p=0.2)。结论远视与球镜测量的窄角膜切迹之间有明显的关联,与远视的严重程度无关。因此,建议对这些患者群体进行狭角筛查。
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引用次数: 0
Comparison of “Van Herick’s” method versus “Borrone’s” method for estimating narrow angles 范-赫利克 "法与 "博罗内 "法在估算窄角方面的比较
Pub Date : 2024-02-02 DOI: 10.15406/aovs.2024.14.00455
Perez Mauricio, Barrera Piero, Basso Gigliola, Perez Matías
Background: Strategies for indirectly assessing the iridocorneal angle aim to be reproducible, reliable, and comparable to gonioscopy for screening in cases of narrow angles and their clinical spectrum. Objectives: The objective of this study is to determine which of the indirect estimation methods of the iridocorneal angle, either the "Van Herick" method or the "Borrone" method, exhibits a higher correlation with gonioscopy in detecting narrow iridocorneal angles in patients at the Ophthalmology outpatient clinic of the Hospital San Borja Arriarán. Materials and methods: A cross-sectional study was conducted with a sample of 32 patients (64 eyes) who met the inclusion and exclusion criteria. Results were obtained through gonioscopy, identifying narrow angles in 16 eyes and open angles in 48 eyes. Sensitivity and specificity of both methods (Borrone and Van Herick) were calculated in comparison to gonioscopy, using a selected cutoff point. Results: The Borrone method showed a sensitivity of 96% and a specificity of 91%, with a 95% confidence interval, compared to gonioscopy. In contrast, the Van Herick method demonstrated a sensitivity of 77% and a specificity of 82% in relation to gonioscopy. Discussion: The high sensitivity and specificity of the “Borrone” method are attributed to its technical details and its dichotomous nature, making it easier for the operator to determine and interpret. This reduces variability and provides a high correlation with gonioscopy. Conclusions: In this study, the “Borrone” method was found to have a more significant correlation with gonioscopy compared to the “Van Herick” method. Therefore, the “Borrone” method is considered more reliable and reproducible for detecting possible narrow iridocorneal angles, especially in high patient volume settings, such as ophthalmology outpatient clinics.
背景:间接评估虹膜角的策略应具有可重复性、可靠性,并可与眼底镜检查相媲美,以筛查虹膜角狭窄的病例及其临床表现。研究目的本研究的目的是确定 "Van Herick "法和 "Borrone "法中哪一种虹膜角膜间接估测法与验光法在检测圣博尔哈-阿里亚兰医院眼科门诊病人的虹膜角膜狭小方面具有更高的相关性。材料和方法:对符合纳入和排除标准的 32 名患者(64 只眼睛)进行了横断面研究。结果通过眼底镜检查得出,16 只眼睛为窄角,48 只眼睛为开角。使用选定的临界点计算了两种方法(Borrone 和 Van Herick)与眼底镜检查的敏感性和特异性。结果显示在 95% 的置信区间内,与眼底镜检查相比,Borrone 方法的灵敏度为 96%,特异性为 91%。相比之下,Van Herick 方法与眼底镜检查相比,灵敏度为 77%,特异性为 82%。讨论:Borrone "方法的高灵敏度和特异性归功于其技术细节和二分法的性质,使操作者更容易判断和解释。这减少了变异性,并与眼底镜检查高度相关。结论本研究发现,"Borrone "法与 "Van Herick "法相比,与眼底镜检查的相关性更显著。因此,"Borrone "法被认为在检测可能存在的虹膜角膜窄时更可靠,可重复性更高,尤其是在病人较多的情况下,如眼科门诊。
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引用次数: 0
Suspected glaucoma: who is who? 疑似青光眼:谁是谁?
Pub Date : 2024-01-08 DOI: 10.15406/aovs.2024.14.00453
Mauricio Pérez González, Marcelo Vega Codd, Matías Perez Miranda, Gabriel Espinoza Torres
Glaucoma is the second cause of blindness worldwide, being the first cause of irreversible blindness. It is estimated that in 2040 there will be around 111.8 million patients with glaucoma, reaching a 3.5% prevalence in patients between 40 and 80 years old; This situation can be preventable if we can identify early the cases at risk of developing the disease, who correspond to the suspected diagnosis of glaucoma.
青光眼是导致全球失明的第二大原因,也是导致不可逆转性失明的第一大原因。据估计,到 2040 年,青光眼患者将达到约 1.118 亿人,在 40 岁至 80 岁的患者中发病率将达到 3.5%。
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引用次数: 0
Evaluation of microsplatter produced during mechanical in-office lid hygiene treatments 办公室内机械盖子卫生处理过程中产生的微飞溅的评价
Pub Date : 2023-07-26 DOI: 10.15406/aovs.2023.13.00445
John Olkowski MD
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引用次数: 0
Uveopathies: a new look at etiopathogenesis and treatment 葡萄膜病:病因和治疗的新视角
Pub Date : 2023-06-28 DOI: 10.15406/aovs.2023.13.00444
Rudkovska Oksana Dmytrivna
Currently, the cause of uveopathies is unknown, there is no radical treatment. The final of these diseases is blindness from glaucoma. The author developed a hypothesis of the etiopathogenesis of uveopathies, according to which the trigger of these diseases is the weakness of accommodation caused by the genetically determined excessively small distance between the ciliary body and the equator of the lens. The following approaches to solving the problem of uveopathies are proposed: a). formation of laser mydriasis (at the initial stages of the process); b). surgical expansion of the ring of the ciliary body - the formation of supraciliary non-penetrating sclerectomies (imitation of anterior staphyloma of the sclera in neglected myopia and glaucoma); in). phacoemulsification of the lens with IOL implantation (optimal final refraction of the artificial eye - simple myopic direct type astigmatism up to 1.5 diopters). It is assumed that these operations will affect the trigger of uveopathy - a genetically determined weakness of accommodation, Uveopathies (Fuchs' syndrome, essential mesodermal progressive dystrophy of the iris, glaucoma-cyclitic crisis) are not fully understood diseases.
目前,葡萄膜病的病因尚不清楚,没有根治方法。最后一种疾病是青光眼导致的失明。作者提出了一种关于葡萄膜病发病机制的假说,根据该假说,这些疾病的诱因是由遗传决定的睫状体与晶状体赤道之间的距离过小而引起的调节能力不足。本文提出了以下解决葡萄膜病的方法:a)形成激光瞳孔(在过程的初始阶段);B).睫状体环的手术扩张-睫状体上非穿透性巩膜切除术的形成(模仿被忽视的近视和青光眼的巩膜前葡萄肿);在)。人工晶状体超声乳化植入术(人工眼最佳最终屈光度-单纯性近视直接型散光达1.5屈光度)。据推测,这些手术将影响葡萄膜病的触发因素——一种由基因决定的适应性缺陷,葡萄膜病(Fuchs综合征、原发性中胚层进行性虹膜营养不良、青光眼周期性危象)尚未完全被了解。
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引用次数: 0
Light adjustable lens in a post-lasik patient 光可调晶状体在lasik术后患者中的应用
Pub Date : 2023-06-27 DOI: 10.15406/aovs.2023.13.00443
Nicholas J Bruns
The Light Adjustable Lens is a newly approved lens that can be altered in-vivo after cataract surgery to address residual refractive error. This is done through highly specific ultraviolet light applications two weeks post-operatively. Patients require 2-5 total light adjustments. The ability to adjust the lens allows patients to more confidently participate in the surgical process while customizing their refractive status. Patients who have previously undergone corneal refractive surgery can provide an added challenge to cataract surgeons. Because of induced changes in corneal structure, intraocular lens calculations can be more difficult, ultimately leading to variability in refractive outcome. The light adjustable lens is sure to change how surgeons and optometrists counsel and manage patients pre- and post-operatively. The case described below details the structure and functionality of the light adjustable lens as well as a clinical application in a post-LASIK patient.
光可调晶状体是一种新批准的晶状体,可以在白内障手术后体内改变,以解决残余屈光不正。这是在术后两周通过高度特异的紫外线照射完成的。患者需要2-5个总光调节。调整晶状体的能力使患者能够更自信地参与手术过程,同时定制他们的屈光状态。以前接受过角膜屈光手术的患者对白内障外科医生来说是一个额外的挑战。由于角膜结构的改变,人工晶状体的计算变得更加困难,最终导致屈光结果的变化。这种可调光的镜片肯定会改变外科医生和验光师在术前和术后对患者的建议和管理。本病例详细介绍了可调光晶状体的结构和功能,以及在lasik术后患者中的临床应用。
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引用次数: 0
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Advances in Ophthalmology &amp; Visual System
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