[Biodemographic parameters as indicators of genetic adaptation to harmful occupational factors (e.g. asbestos)].

G V Tsurikova, V A Spitsyn, E V Gladkova, O P Minaeva
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Abstract

A total of 129 women working at asbestos-concentrating factories and asbestos articles manufacture plant, including 87 of them facing asbestosis and 42 exposed to asbestos without asbestosis were examined. There was no marked shifts in the reproductive function and pregnancy results of women facing asbestosis and those exposed to asbestos without asbestosis. Women facing asbestosis has infant mortality higher than other women. Parameters of potential selection (index Crow) in the studied population showed an unfavourable demographic situation in women facing asbestosis. Analysis of biodemographic data helped to suggest the possibility of genetic predisposition to asbestosis.

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[作为遗传适应有害职业因素(如石棉)指标的生物人口学参数]。
对在石棉浓缩工厂和石棉制品制造厂工作的129名妇女进行了检查,其中87人面临石棉沉滞症,42人接触石棉,但没有石棉沉滞症。面对石棉沉滞症的妇女和接触石棉但没有石棉沉滞症的妇女的生殖功能和怀孕结果没有明显变化。患有石棉沉滞症的妇女的婴儿死亡率高于其他妇女。研究人群的潜在选择参数(指数Crow)显示,面临石棉沉滞症的妇女的人口状况不利。对生物统计学数据的分析有助于提出石棉沉滞的遗传易感性的可能性。
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