[Mutagenic activity of the azo dye Disperse Orange 2K and its basic component Reax dispenser].

Gigiena truda i professional'nye zabolevaniia Pub Date : 1992-01-01

S E Khipko, L I Paranich, V I Zvezdaĭ, G D Starchenko, N A Vashchuk

引用次数: 0

Abstract

Mutagenic activity of inhaled dispersed orange 2K nitrodye (DON 2K) and Reax' disperser was evaluated. Chronically inhaled DON 2K (with disperser) in concentration 28.6 mg/m3 is a genetic danger for an individual and population, being also a selective by injurious++ to the red blood cells. Chronically inhaled Reax' disperser (25.7 and 5.8 mg/m3) shows low mutagenic activity in somatic tissue. Thus, the mutagenic effect of DON 2K with disperser (composition is constant) is explained by nitrodye and not a disperser.

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偶氮染料分散橙2K及其基本组分Reax点胶剂的诱变活性。

对吸入分散橙色2K硝基染料(DON 2K)和Reax分散剂的致突变性进行了评价。长期吸入浓度为28.6 mg/m3的DON 2K(含分散剂)对个体和群体具有遗传危险，同时对红细胞具有选择性损伤。慢性吸入的Reax分散剂(25.7和5.8 mg/m3)在体细胞组织中表现出较低的致突变活性。因此，分散剂(组成不变)对DON 2K的诱变作用是由硝基染料而不是分散剂来解释的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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