Current synthesis routes of thiazole and its derivatives and their broad spectrum therapeutic activity: A Review

Nadeem Alam, S. Arora, Asiya Ibrahim, Pallavi Deval
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引用次数: 1

Abstract

Thiazole is an important nucleus owing to its wide range of medical uses. It contains components that are anti-bacterial, anti-fungal, anti-malarial, anti-cancer, anti-allergic, anti-hypertensive, anti-inflammatory, and anti-psychotic, as well as antioxidant, analgesic, and antimicrobial. The thiazole scaffold has been detected in the more than eighteen FDA-accepted medicines in addition to countless research compounds. A literature review on this themes was undertaken from 2015 to the present. Older publications were not investigated since they had already been peer reviewed.
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噻唑及其衍生物的合成途径及其广谱治疗活性综述
由于其广泛的医学用途,噻唑是一种重要的原子核。它含有抗菌、抗真菌、抗疟疾、抗癌、抗过敏、抗高血压、抗炎、抗精神病以及抗氧化、镇痛、抗菌等成分。除了无数的研究化合物外,噻唑支架已经在超过18种fda认可的药物中被检测到。从2015年至今,我们对这一主题进行了文献综述。较早的出版物没有被调查,因为它们已经经过了同行评审。
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