[Neuropsychological changes in drug addicts infected with human immunodeficiency virus].

Archivos de neurobiologia Pub Date : 1992-09-01
P Sopelana, M Débora, S López-Calvo, J C García-Alvarez, C Polo
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Abstract

The early organic mental disorder, caused by the human immunodeficiency virus type 1 (HIV) in the drug dependents (DD), if it is not taken into account, can disturb the diagnosis of the neuropsychiatric and the toxic disorders. The authors attempt to outline, with several neuropsychological tests (visuo-perceptual, memory, attention) and with the physical and neurologic exploration, if cognitive abnormalities are present in two groups of DD after detoxification period. The first group is infected by the HIV (n: 48), and the second one is not (n: 33). Differences can be found only in the Bender visuo-perceptual test, which are not justified by the divergences found between the groups about the drug dependence history and the present drug of abuse intake. The importance of the early diagnosis of these abnormalities is argued in order to get a suitable treatment of the possible neuropsychiatric complications in the DD development, and restrain the extent of the cognitive damage by HIV infection.

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[感染人类免疫缺陷病毒的吸毒者的神经心理变化]。
早期器质性精神障碍是由人类免疫缺陷病毒1型(HIV)在药物依赖者(DD)中引起的,如果不加以考虑,可能会干扰神经精神疾病和毒性疾病的诊断。作者试图通过几项神经心理学测试(视觉知觉、记忆、注意力)以及物理和神经学探索来概述两组DD在解毒期后是否存在认知异常。第一组感染了艾滋病毒(n: 48),第二组没有(n: 33)。仅在Bender视觉知觉测试中可以发现差异,这并不能被两组药物依赖史和目前滥用药物摄入的差异所证明。本文认为早期诊断这些异常的重要性,有助于对DD发展过程中可能出现的神经精神并发症进行适当的治疗,并抑制HIV感染引起的认知损害程度。
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