A treatment engine by multimodal EMR data

Zhaomeng Huang, Liyan Zhang, Xu Xu
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Abstract

In recent years, with the development of electronic medical record (EMR) systems, it has become possible to mine patient clinical data to improve medical care quality. After the treatment engine learns knowledge from the EMR data, it can automatically recommend the next stage of prescriptions and provide treatment guidelines for doctors and patients. However, this task is always challenged by the multi-modality of EMR data. To more effectively predict the next stage of treatment prescription by using multimodal information and the connection between the modalities, we propose a cross-modal shared-specific feature complementary generation and attention fusion algorithm. In the feature extraction stage, specific information and shared information are obtained through a shared-specific feature extraction network. To obtain the correlation between the modalities, we propose a sorting network. We use the attention fusion network in the multimodal feature fusion stage to give different multimodal features at different stages with different weights to obtain a more prepared patient representation. Considering the redundant information of specific modal information and shared modal information, we introduce a complementary feature learning strategy, including modality adaptation for shared features, project adversarial learning for specific features, and reconstruction enhancement. The experimental results on the real EMR data set MIMIC-III prove its superiority and each part's effectiveness.
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多模态电子病历数据处理引擎
近年来,随着电子病历(EMR)系统的发展,对患者临床数据的挖掘,提高医疗质量成为可能。治疗引擎从EMR数据中学习知识后,可以自动推荐下一阶段的处方,为医生和患者提供治疗指南。然而,电子病历数据的多模态对这一任务提出了挑战。为了利用多模态信息和模态之间的联系更有效地预测下一阶段的治疗处方,我们提出了一种跨模态共享特异性特征互补生成和注意融合算法。在特征提取阶段,通过共享特征提取网络获得特定信息和共享信息。为了获得模态之间的相关性,我们提出了一个排序网络。我们利用多模态特征融合阶段的注意融合网络,在不同阶段赋予不同的多模态特征不同的权重,以获得更有准备的患者表征。考虑到特定模态信息和共享模态信息的冗余性,提出了一种互补的特征学习策略,包括针对共享特征的模态自适应、针对特定特征的项目对抗学习和重构增强。在真实EMR数据集MIMIC-III上的实验结果证明了该方法的优越性和各部分的有效性。
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