Resonant based microwave biosensor for biological cells discrimination

K. Grenier, D. Dubuc, P. Poleni, M. Kumemura, H. Toshiyoshi, T. Fujii, H. Fujita
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引用次数: 33

Abstract

This publication deals with a resonant RF-based biosensor for in-liquid operation. Stop-band filter modeling and characterizations are investigated in order to discriminate dead and alive suspensions of human cultured cells. This proof of concept demonstrator features noticeable contrasts on both resonant frequency (7%) and amplitude (2.1 dB). Theses results consequently demonstrate that RF detection can provide a non invasive sensing technique, which is compatible with a lab-on-a-chip approach to discriminate the pathological state of cells.
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基于共振的微波生物传感器用于生物细胞识别
本出版物涉及一种用于液体操作的基于射频共振的生物传感器。为了区分人培养细胞的死悬液和活悬液,研究了阻带滤波器的建模和表征。这个概念验证演示器在共振频率(7%)和幅度(2.1 dB)上都有明显的对比。这些结果表明,射频检测可以提供一种非侵入式传感技术,与芯片实验室方法兼容,可以区分细胞的病理状态。
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