Modeling and analysis of ultrasonic cavitation for permeation enhancement

Tangtang Lou, C. Bai, Peiyu Zhang
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Abstract

The growth and collapse of acoustic (ultrasonic) cavitation bubbles have an important influence on the permeable properties of fluid or human tissue. The influence mechanism needs further research. The dynamic model of acoustic cavitation bubbles induced by mix frequencies was built based on the Rayleigh-Plesset equation. The growth and collapse of acoustic cavitation were modeled and the movements of the interface were analyzed. The different radius and frequencies of acoustic cavitation bubbles were simulated. The suitable combination both low and high frequencies can enhance the ultrasonic cavitation and therefore profit permeation enhancement to human tissue.
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超声空化增透的建模与分析
声(超声)空化泡的生长和破裂对流体或人体组织的渗透特性有重要影响。影响机制有待进一步研究。基于Rayleigh-Plesset方程,建立了混合频率诱导声空化气泡的动力学模型。模拟了声空化的生长和破裂过程,分析了界面的运动。模拟了不同半径和频率的声空化气泡。适当的低频和高频组合可以增强超声空化,从而有利于增强对人体组织的渗透。
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