Association of glycolytic enzymes with the cytoskeleton.

H R Knull, J L Walsh
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引用次数: 132

Abstract

The diverse physical associations of the glycolytic enzymes with structural components of the cell suggest that the glycolytic enzymes are not entirely soluble in the cell. The relatively low affinities of the associations are likely responsible for the apparently transient interactions. The binding phenomenon is suggested to regulate metabolism through changes in enzymatic activity and facilitates localized enrichment of the enzymes.

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糖酵解酶与细胞骨架的关联。
糖酵解酶与细胞结构组分的不同物理关联表明糖酵解酶并非完全可溶于细胞。这种关联的相对较低的亲和力可能是造成这种表面上短暂的相互作用的原因。这种结合现象被认为是通过改变酶的活性来调节代谢,并促进酶的局部富集。
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