N. Okada, O. Sugita, T. Miida, Y. Makino, N. Komoro
{"title":"Endothelial cell responses to controlled pulsatile flow at the bifurcation of a model vessel","authors":"N. Okada, O. Sugita, T. Miida, Y. Makino, N. Komoro","doi":"10.1109/IEMBS.1994.412039","DOIUrl":null,"url":null,"abstract":"The authors exposed endothelial cells of the porcine aorta to different flow conditions using a model vessel. This model is made of glass tube and consists of a main tube and a side branch of which angle is 90/spl deg/. The shear rate of the main tube was 20 sec/sup -1/, while that of the side branch was 29 sec/sup -1/. Lactic dehydrogenase (LDP) was measured as an indicator of cell damage. Changes of LDH from cultured cells in dishes by adding native lipoprotein, oxidized and non-oxidized linoleic acid were also examined for comparisons. LDH was lower in the cells of the side branch than in those of the main tube.<<ETX>>","PeriodicalId":344622,"journal":{"name":"Proceedings of 16th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"8 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1994-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of 16th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IEMBS.1994.412039","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The authors exposed endothelial cells of the porcine aorta to different flow conditions using a model vessel. This model is made of glass tube and consists of a main tube and a side branch of which angle is 90/spl deg/. The shear rate of the main tube was 20 sec/sup -1/, while that of the side branch was 29 sec/sup -1/. Lactic dehydrogenase (LDP) was measured as an indicator of cell damage. Changes of LDH from cultured cells in dishes by adding native lipoprotein, oxidized and non-oxidized linoleic acid were also examined for comparisons. LDH was lower in the cells of the side branch than in those of the main tube.<>
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