Paracetamol as Analgesia Following Spontaneous Vaginal Delivery: Reappraisal of Practice

Nur Farihan Mukhtar, Amanina Syamim Ahmad Nazli, Muhammad Ashraf Ahmad, Norafifah Suboh
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Abstract

Background: We aim to determine the prevalence of perineal pain following postpartum vaginal delivery, the requirement of paracetamol as analgesia, and its associated factors. Methods: The study was performed from December 14, 2020, until February 14, 2021, in a single tertiary centre in northwest Malaysia. The pain score was assessed immediately postpartum and every six hours for the next 48 hours, and the requirement for paracetamol as analgesia was documented. Maternal sociodemographic data and baseline clinical details associated with the requirement for paracetamol were analysed. Results: A total of 285 study participants were included. The majority (93.0%) were Malays, with a mean age of 31.0 6.08 years. Majority of the women delivered their second child (36.1%) with a first-degree tear (46.7%). The majority neither required any analgesia within the first few hours of delivery in the labour room (71.3%) nor in the next 48 hours of ward observation (54.4%). The mean pain score following spontaneous vaginal delivery in the labour room was 4.0 1.07, while the mean pain score in the ward was 2.8 ± 1.05 (p<0.001). Logistic regression analysis determined that maternal weight (cOR: 1.02, 95% CI: 1.01, 1.04) and episiotomy (cOR: 3.28, 95% CI: 1.52, 7.08) were significantly predictive of paracetamol requirement as analgesia. Conclusion: Most of our population did not require oral analgesia in the postpartum period. However, the identification of susceptible individuals may guide clinicians to have a targeted approach for early management to ensure a positive birthing experience for all mothers.
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对乙酰氨基酚作为阴道自然分娩后的镇痛:实践的重新评价
背景:我们的目的是确定产后阴道分娩后会阴疼痛的患病率,扑热息痛作为镇痛的需求及其相关因素。方法:该研究于2020年12月14日至2021年2月14日在马来西亚西北部的一个单一三级中心进行。产后立即评估疼痛评分,在接下来的48小时内每6小时评估一次疼痛评分,并记录对乙酰氨基酚作为镇痛药的需求。分析了与扑热息痛需求相关的产妇社会人口统计数据和基线临床细节。结果:共纳入285名研究参与者。大多数(93.0%)是马来人,平均年龄为31.0 - 6.08岁。大多数妇女分娩二胎时伴有一级撕裂(46.7%)(36.1%)。大多数产妇在产房分娩后数小时内(71.3%)和随后48小时的病房观察内(54.4%)均不需要任何镇痛。产房自然分娩后疼痛平均评分为4.0 1.07分,病房疼痛平均评分为2.8±1.05分(p<0.001)。Logistic回归分析表明,产妇体重(比值比:1.02,95% CI: 1.01, 1.04)和外阴切开术(比值比:3.28,95% CI: 1.52, 7.08)与镇痛对乙酰氨基酚需要量有显著相关性。结论:大多数产妇在产后不需要口服镇痛。然而,易感个体的识别可以指导临床医生有针对性的方法进行早期管理,以确保所有母亲的积极分娩体验。
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