Medulloblastoma

Asifur Rahman
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Abstract

Among the pediatric brain tumors, medulloblastoma (MB) is the most common solid variety and entirely occur in the posterior fossa with tendency to seed into CSF spaces. Despite innovations in technological developments and understanding of tumor biology, modern imaging facilities, advances in surgical practices, and newer chemotherapeutic and radiation techniques, this malignant type of tumor continues to be a formidable entity. Even though, the outcome in terms of survival rate is better than any time before, the overall result is still disappointing. With advances in management strategy, chances of survival with good quality of life have been amplified, where newer targeted thera pies and rehabilitation plays an immense role. While the adverse effects of surgery and adjuvant therapies are still on play, researchers are trying ceaselessly to minimize those to give maximum wellbeing to these unfortunate children.
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成神经管细胞瘤
在儿童脑肿瘤中,髓母细胞瘤(MB)是最常见的实性肿瘤,完全发生于后窝,有向脑脊液间隙播散的趋势。尽管在技术发展和对肿瘤生物学的理解、现代成像设备、外科实践的进步以及更新的化疗和放疗技术方面有了创新,这种恶性肿瘤仍然是一个令人生畏的实体。尽管在存活率方面的结果比以往任何时候都好,但总体结果仍然令人失望。随着管理策略的进步,生活质量良好的生存机会已经扩大,其中新的针对性治疗和康复发挥了巨大的作用。虽然手术和辅助治疗的副作用仍在发挥作用,但研究人员正在不断努力将其最小化,以最大限度地为这些不幸的孩子带来幸福。
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