{"title":"Γ","authors":"Τρίγκας Μάριος, Παπαδόπουλος Ιωάννης, ταλός Γεώργιος, Καραγκούνη, Γλυκερία, Σιδεράς Αδαμάντιος, Ονουφρίου Αντρέας","doi":"10.1515/9783112448489-003","DOIUrl":null,"url":null,"abstract":"Coronavirus disease 2019 (COVID-19) is characterized by a pro-inflammatory state associated with organ failure, thrombosis, and death. We investigated a novel inflammatory biomarker, γ ′ fibrinogen (GPF), in 103 hospitalized patients with COVID-19 and 19 healthy controls. We found significant associations between GPF levels and the severity of COVID-19 as judged by blood oxygen saturation (SpO 2 ). The mean level of GPF in the patients with COVID-19 was significantly higher than in controls (69.8 (95 % CI 64.8 – 74.8) mg/dL compared with 36.9 (95 % CI 31.4 – 42.4) mg/dL, p < 0.0001), whereas C-reactive protein (CRP), lactate dehydrogenase (LDH)","PeriodicalId":222522,"journal":{"name":"Platonis dialogi graece et latine Partis 3, Volumen 1","volume":"35 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1817-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Platonis dialogi graece et latine Partis 3, Volumen 1","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1515/9783112448489-003","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Coronavirus disease 2019 (COVID-19) is characterized by a pro-inflammatory state associated with organ failure, thrombosis, and death. We investigated a novel inflammatory biomarker, γ ′ fibrinogen (GPF), in 103 hospitalized patients with COVID-19 and 19 healthy controls. We found significant associations between GPF levels and the severity of COVID-19 as judged by blood oxygen saturation (SpO 2 ). The mean level of GPF in the patients with COVID-19 was significantly higher than in controls (69.8 (95 % CI 64.8 – 74.8) mg/dL compared with 36.9 (95 % CI 31.4 – 42.4) mg/dL, p < 0.0001), whereas C-reactive protein (CRP), lactate dehydrogenase (LDH)
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