Prediction of Multi-site Protein Subcellular Localization

Abstract

Multi-site protein subcellular localization prediction has close relationship with protein function, metabolic and transduction between signals. It can play an important role in speculating the biological function of protein, clearing the gene function and clarifying the internal mechanism of diseases. As some proteins located in two or more subcellulars at the same time, it is necessary for us to do the research on multi-site protein subcellular localization prediction. This paper reviewed the problem from the following four aspects, dataset construction, protein features extraction, predicting algorithm and algorithm evaluation.