Effect of Insulin Resistance on Left Ventricular Remodeling in Essential Hypertensives: A Cross Sectional Study

K. P. Bernard, N. Aliocha, Kintoki, Vita Eleuthère, L. Benjamin, M’Buyamba, Kabangu Jean-René
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Abstract

In clinical practice, left ventricular hypertrophy is defined not by the left ventricular walls thickness, but by the left ventricular mass. The later is calculated according to the Devereux's formula, and is increased by insulin resistance/hyperinsulinemia. It is however unclear which of insulin resistance, hyperinsulinemia, or both is actually causative and what is their collective or individual influence on the components of Devereux's formula and parameters of left ventricular diastolic function. Thepresent study evaluated the associations ofthe Homeostatic Model Assessment for Insulin Resistance (HOMAIR) and fasting plasma insulinwith components of Devereux's formula and parameters of left ventricular diastolic function.
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胰岛素抵抗对原发性高血压左心室重构的影响:一项横断面研究
在临床实践中,左室肥厚不是由左室壁厚度来定义的,而是由左室质量来定义的。后者根据Devereux公式计算,并因胰岛素抵抗/高胰岛素血症而增加。然而,目前尚不清楚胰岛素抵抗、高胰岛素血症或两者中哪一个是真正的病因,以及它们对Devereux公式成分和左室舒张功能参数的集体或个人影响。本研究评估了胰岛素抵抗稳态模型评估(HOMAIR)和空腹血浆胰岛素与Devereux公式成分和左心室舒张功能参数的关系。
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Effect of Insulin Resistance on Left Ventricular Remodeling in Essential Hypertensives: A Cross Sectional Study Prevalence and Determinants of Insulin Resistance in Asymptomatic Black Congolese with Essential Hypertension: A Cross-Sectional Study
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