The proportion of Hypothyroid in Type 2 Diabetes Mellitus Patients in Dr. Hasan Sadikin Hospital

Armina Latifah, N. Tristina, Fajar Wasilah
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引用次数: 1

Abstract

Type 2 Diabetes Mellitus (T2DM) and thyroid dysfunction often coexist. Both diseases have overlapping pathomechanisms and increased risk along with advanced age. The prevalence of hypothyroidism in patients with T2DM is 12%-15% compared to 1.3%-4.6% of the general population. Glycemic control is an essential factor in developing hypothyroidism. Thyroid Stimulating Hormone (TSH) levels are used to diagnose hypothyroidism because subclinical hypothyroidism commonly shows normal T4 and T3 levels. This study aimed to measure TSH levels in patients with T2DM. The study design was observational, descriptive, and cross-sectional. Researchers carried out TSH measurements by using leftover samples from T2DM patients. Subjects were recruited by consecutive sampling. The inclusion criteria were subjects > 35 years old who were diagnosed with T2DM. The exclusion criteria were subjects who were previously diagnosed with hyperthyroidism or hypothyroidism. This study found that 11% of 71 subjects had elevated TSH levels. The subjects were 32 (45%) male and 39 (55%) female patients aged 38-72 years. Subjects with high TSH levels were between the ages of 49 and 72. There were 5 of 8 subjects (62.5%) with elevated TSH levels and poor glycemic control. The prevalence of hypothyroidism in T2DM was 11%. Thyroid stimulating hormone is recommended for T2DM, especially in patients over 50 with poor glycemic control.
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Dr. Hasan Sadikin医院2型糖尿病患者甲状腺功能减退的比例
2型糖尿病(T2DM)常与甲状腺功能障碍并存。这两种疾病具有重叠的病理机制,并且随着年龄的增长风险增加。T2DM患者甲状腺功能减退的患病率为12%-15%,而普通人群的患病率为1.3%-4.6%。血糖控制是甲状腺功能减退的重要因素。促甲状腺激素(TSH)水平用于诊断甲状腺功能减退症,因为亚临床甲状腺功能减退症通常显示正常的T4和T3水平。本研究旨在测量T2DM患者的TSH水平。研究设计为观察性、描述性和横断面。研究人员使用T2DM患者的剩余样本进行TSH测量。采用连续抽样的方法招募受试者。纳入标准为年龄> 35岁且诊断为T2DM的受试者。排除标准是以前被诊断为甲状腺功能亢进或甲状腺功能减退的受试者。这项研究发现,71名受试者中有11%的人TSH水平升高。研究对象为男性32例(45%),女性39例(55%),年龄38 ~ 72岁。TSH水平高的受试者年龄在49岁到72岁之间。8名受试者中有5名(62.5%)TSH水平升高且血糖控制不良。T2DM患者甲状腺功能减退的患病率为11%。2型糖尿病推荐使用促甲状腺激素,尤其是50岁以上血糖控制不良的患者。
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