{"title":"Thoughts for the Future","authors":"R. McCarty","doi":"10.1093/med-psych/9780190697266.003.0016","DOIUrl":null,"url":null,"abstract":"Several exciting lines of research have emerged from the study of animal models of mental disorders. This chapter presents seven opportunities for enhancing the diagnosis and treatment of mental disorders. They include improvements to the system for diagnosis of mental disorders, use of induced pluripotent stem cells from patients to generate neuronal cultures for in vitro determination of effective drug therapies for those individuals, use of data-mining techniques for understanding patient variability, a commitment to a greater focus on the prevention of mental disorders, innovative uses of smartphones to track patients and individuals at high risk of developing a mental disorder, and developing next-generation therapies and delivery systems that target a specific area of the brain rather than the entire brain. A common theme in these seven thoughts for the future is a commitment to bringing precision medicine tools to the treatment of patients with mental disorders.","PeriodicalId":251581,"journal":{"name":"Stress and Mental Disorders: Insights from Animal Models","volume":"38 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Stress and Mental Disorders: Insights from Animal Models","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/med-psych/9780190697266.003.0016","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract

Several exciting lines of research have emerged from the study of animal models of mental disorders. This chapter presents seven opportunities for enhancing the diagnosis and treatment of mental disorders. They include improvements to the system for diagnosis of mental disorders, use of induced pluripotent stem cells from patients to generate neuronal cultures for in vitro determination of effective drug therapies for those individuals, use of data-mining techniques for understanding patient variability, a commitment to a greater focus on the prevention of mental disorders, innovative uses of smartphones to track patients and individuals at high risk of developing a mental disorder, and developing next-generation therapies and delivery systems that target a specific area of the brain rather than the entire brain. A common theme in these seven thoughts for the future is a commitment to bringing precision medicine tools to the treatment of patients with mental disorders.
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对未来的思考
在对精神障碍动物模型的研究中出现了一些令人兴奋的研究方向。本章提出了加强精神障碍诊断和治疗的七个机会。它们包括对精神障碍诊断系统的改进,使用来自患者的诱导多能干细胞来产生神经元培养物,以便在体外确定对这些个体有效的药物治疗,使用数据挖掘技术来了解患者的可变性,承诺更加关注精神障碍的预防,创新地使用智能手机来跟踪患者和患精神障碍的高风险个体,开发针对大脑特定区域而不是整个大脑的下一代疗法和输送系统。这七个想法中有一个共同的主题,那就是致力于为精神障碍患者的治疗带来精准医疗工具。
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