ABREVIATURAS

João Paulo Lopes da Cunha, Susana Maria Sampaio, Pacheco Pereira de Oliveira, Julieta Maria Pereira
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Abstract

The evolution of the health sector in recent decades has guaranteed to the population increasingly innovative and more complex technologies. This led to the achievement of considerable health gains, increasing the life span of the population, as well as the years lived with quality. However, these developments have led to an increase in health spending in different countries, raising the need to look for strategies that ensure the population's access to the best available therapy, at the best cost. Based on the premise of bioequivalence, generic medicines are a vital tool to achieve this goal, because they allow the reduction of charges with therapies that have already lost exclusivity, releasing funds for therapeutic innovation. Using Rogers' theory of diffusion of innovation, this work tries to evaluate, for the Portuguese market, the differences between molecules with high and low consumption of generic drugs, what influence the diffusion determinants exert on the adoption of these drugs in 2016 and how access to them is conditioned by the time of entry. Using as a sample the molecules with the highest and lowest consumption of generic drugs, in 2016, in Portugal, the study intends to answer the previous questions using the statistical analysis of the determinants of the diffusion theory and the estimation of a linear regression model. The results demonstrate that the molecules with the highest consumption of generics have been in the market for the longest time, have a higher level of intramolecular competition and have a lower relative price of these drugs. In addition, the potential differentiation of the original drug and intramolecular competition appear to have statistically significant effects ( p <0.05) on the consumption of generic drugs in 2016. Moreover, in Portugal these drugs still take a long time to enter the market, conditioning its potential in reducing health expenditure.
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近几十年来卫生部门的发展为人民提供了越来越多的创新和更复杂的技术。这导致取得了相当大的健康成果,延长了人口的寿命,提高了生活质量。然而,这些发展导致不同国家的卫生支出增加,因此需要寻找确保人民以最优费用获得现有最佳治疗的战略。基于生物等效性的前提,仿制药是实现这一目标的重要工具,因为它们可以降低已经失去独占性的疗法的收费,为治疗创新释放资金。利用罗杰斯的创新扩散理论,本研究试图评估葡萄牙市场中仿制药高消费量和低消费量分子之间的差异,扩散决定因素对2016年这些药物的采用产生了什么影响,以及如何根据进入时间获得这些药物。本研究以2016年葡萄牙仿制药消费量最高和最低的分子为样本,利用扩散理论决定因素的统计分析和线性回归模型的估计来回答上述问题。结果表明,仿制药消费量最高的分子上市时间最长,分子内竞争程度较高,相对价格较低。此外,原研药潜在差异化和分子内竞争对2016年仿制药消费的影响具有统计学意义(p <0.05)。此外,在葡萄牙,这些药物仍然需要很长时间才能进入市场,制约了其在减少卫生支出方面的潜力。
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LA POSESIÓN, COMERCIALIZACIÓN, TRÁFICO Y SUMINISTRO DE SUSTANCIAS Y MÉTODOS CON FINES DE DOPAJE Y OTRAS CONDUCTAS ANÁLOGAS (RÉGIMEN DISCIPLINARIO) PRÓLOGO ABREVIATURAS RECAPITULACIÓN Y REFLEXIONES CONCLUSIVAS LA POSESIÓN, COMERCIALIZACIÓN, TRÁFICO Y SUMINISTRO DE SUSTANCIAS Y MÉTODOS CON FINES DE DOPAJE Y OTRAS CONDUCTAS ANÁLOGAS (RÉGIMEN PENAL)
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