Severe Acute Respiratory Syndrome, the First Pandemic of the Twenty-First Century; Middle East Respiratory Syndrome; and the 2019–2020 Outbreak of 2019-nCoV

M. Oldstone
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Abstract

This chapter assesses Severe Acute Respiratory Syndrome (SARS), which represented the first new viral pandemic of the 21st century. Beginning mysteriously in Southern China during November of 2002, this plague was brought under control by 2004, but only after spreading to thirty-three countries on five continents and infecting over eight thousand humans, seven-hundred and seventy-four of whom died. How the disease spread exemplifies the speed and breadth of viral migration today. Then, as mysteriously as it came, SARS disappeared. However, a closely related viruses, Middle East Respiratory Syndrome (MERS), first emerged in the Arabian Peninsula in 2012 and COVID-19 emerged in China in 2019 with both spreading globally. SARS , MERS and CVID-19 are members of the coronavirus family. At present, distinct species of bats have been implicated as natural reservoir for SARS maintaining this viruses in the communities it occupies. Meanwhile, how MERS first infected humans and what the animal carrier is are not clear; the suspects are bats and camels. For COVET-19 bats and civets are the suspects
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严重急性呼吸系统综合症——21世纪的第一次大流行;中东呼吸综合征;以及2019-2020年新型冠状病毒的爆发
本章评估严重急性呼吸系统综合症(SARS),它代表了21世纪第一个新的病毒大流行。这种瘟疫于2002年11月神秘地在中国南方开始,到2004年才得到控制,但只是在蔓延到五大洲的33个国家,感染了8000多人,其中774人死亡之后。这种疾病的传播方式体现了当今病毒迁移的速度和广度。然后,SARS神秘地消失了。然而,一种密切相关的病毒——中东呼吸综合征(MERS)于2012年首次在阿拉伯半岛出现,2019年在中国出现COVID-19,两者都在全球蔓延。SARS、MERS和covid -19都是冠状病毒家族的成员。目前,不同种类的蝙蝠被认为是SARS的天然宿主,在其所在的群落中维持这种病毒。与此同时,MERS最初是如何感染人类的,动物载体是什么,目前还不清楚;嫌疑犯是蝙蝠和骆驼。对于COVET-19来说,蝙蝠和果子狸是嫌疑对象
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