Investigation of Antimicrobial, Antioxidant and Mutagenic Effect Potential of Red Pepper Grown in Adıyaman Province

Yakup Akkoç, M. Arslan, N. Erbil, Z. T. Murathan
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Abstract

In this study, the biochemical, microbiological, mutagenic and antioxidant properties of red pepper (Capsicum annum) grown in 6 districts of Adıyaman province (Kahta, Gerger, Sincik, Samsat, Tut, Gölbaşı) were investigated. The bioactive compounds of Gerger samples and in parallel with antioxidant activity were high. The results of antimicrobial activity showed that Kahta pepper extract exhibited antibacterial activity against Staphylococcus aureus ATCC 6538 with an MIC value of 0.715 mg/ml. The lowest minimum inhibit concentration values in the pepper extracts were obtained in Kahta pepper extract (0.715-1.43 mg ml-1), and the highest MIC values were recorded in Tut pepper extract (1.1525-4.61 mg ml-1). The mutagenic activity results of peppers indicated no mutagenic effect at the doses testes and in the studies carried out on Salmonella typhimurium TA 98 and TA 100 strains and in the absence of S9. Dose dependent increase was recorded on Salmonella typhimurium TA 98 strain of Samsat pepper samples. However, the increase was not statistically significant.
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Adıyaman省红辣椒抗菌、抗氧化和诱变潜力的研究
本研究对Adıyaman省6个地区(Kahta、Gerger、Sincik、Samsat、Tut、Gölbaşı)红辣椒的生化、微生物、诱变和抗氧化性能进行了研究。Gerger样品具有较高的生物活性和抗氧化活性。抑菌活性结果表明,Kahta辣椒提取物对金黄色葡萄球菌ATCC 6538具有抑菌活性,MIC值为0.715 mg/ml。辣椒提取物中抑制浓度最低的是Kahta辣椒提取物(0.715 ~ 1.43 mg ml-1), MIC最高的是Tut辣椒提取物(1.1525 ~ 4.61 mg ml-1)。在不添加S9的情况下,辣椒对鼠伤寒沙门菌ta98和ta100的诱变活性研究结果表明,在不同剂量下,辣椒对鼠伤寒沙门菌ta98和ta100没有诱变作用。辣椒样品中鼠伤寒沙门菌TA 98菌株呈剂量依赖性增加。然而,这一增长在统计学上并不显著。
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