Clinical observations with Paxirasol nasal spray.

Therapia Hungarica (English edition) Pub Date : 1992-01-01
H Szabadka
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Abstract

The effect of Paxirasol nasal spray has been examined in 25 patients by the open method. The goal of the study was to assess and evaluate the clinical effectivity of the product and to observe the eventual side-effects. Among the examined patients 14 were acute and 11 chronic disease cases. In 20 of the 25 patients treated with Paxirasol nasal spray the pathological alteration of the nasal mucosa was controlled, mild alteration persisted in 4 patients, and moderately severe condition in 1 patient. The product significantly improved the viscosity of nasal discharge in all of them. The cessation or moderation of difficult nose blowing improved the general condition of the patients and accelerated recovery. Occasionally manifesting olfactory disorders ceased as well. The treatment needed not be discontinued because of the development of side-effects. Considering the healing tendency difference could be observed between the acute and chronic cases, especially in rhinitis sicca patients who were treated with Paxirasol nasal spray. In 23 of the 25 patients notable improvement of both the subjective and objective symptoms was observed. Paxirasol nasal spray is of value in very frequently occurring diseases of the nasal mucosa accompanied by dehydration. In the majority of acute disease patients the use of the product as monotherapy may result in complete cessation of symptoms.

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帕西拉索尔鼻喷雾剂的临床观察。
采用开放式方法对25例帕西拉索鼻喷雾剂的疗效进行了观察。该研究的目的是评估和评价该产品的临床有效性,并观察最终的副作用。其中急性病14例,慢性病11例。25例患者中,20例鼻黏膜病理改变得到控制,4例轻度改变持续,1例中重度改变。该产品显著改善了所有患者的鼻分泌物粘度。困难擤鼻涕的停止或适度改善了患者的一般情况,加速了康复。偶尔表现出的嗅觉障碍也停止了。治疗不需要因为出现副作用而中断。考虑到急性和慢性鼻炎患者的愈合趋势存在差异,特别是在使用帕西拉索尔鼻喷雾剂治疗的鼻炎患者中。25例患者中有23例主客观症状均有显著改善。帕西拉索鼻喷雾剂对经常发生的伴有脱水的鼻黏膜疾病很有价值。在大多数急性疾病患者中,使用本品作为单一疗法可导致症状完全停止。
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