Clinical Investigations of Percutaneous Vertebroplasty Combined with Intensity-modulated Radiotherapy for Patients with Spinal Metastases

Abstract

Percutaneous Vertebroplasty (PVP) or radiotherapy are used in tumor with bone metastasis. However, The treatment of vertebral metastasis tumor with PVP combined with Intensity-Modulated Radiotherapy (IMRT) are rarely reported. The effectiveness and feasibility of these treatment procedures are initially observed in the article. We retrospectively analyzed the clinical features of 7 patients with vertebral metastases. They all received PVP, and then IMRT (6 MV-X linear at a dose of 40-60Gy). Technical success of PVP was achieved in all patients, and all of them completed the radiotherapy plan successfully. There are no severe complications were observed. They all got pain relief and no pain or fracture were found after PVP combined with IMRT. PVP combined with IMRT seems to be an effective and feasible means to improve the quality of life of patients with tumor vertebral metastasis.