Bacteriological Profile and Antibiotic Sensitivity Pattern in Patients Attending Out Patient Departments with Urinary Tract Infections.

Abstract

Introduction: Urinary tract infections (UTI) are the most common cause of bacterial infections in humans. A variety of organisms are associated with UTI irrespective of whether they are community or hospital acquired. Aim and Objective: The aim of the study was to determine the bacteriological profile and antibiotic sensitivity pattern of organisms causing UTI in patients attending OPD. Materials and Methods: This study was conducted in the Department of Microbiology, Sri Siddhartha Medical College, Tumakuru from Jan 2017 Mar 2017. All suspected cases of UTI sent for urine culture were tested, bacteriological profile and antibiotic sensitivity pattern was evaluated. Results: A total of 392 clinically suspected cases of UTI of all ages and both sexes were studied. Among the 392 samples, 154 samples yielded significant growth, among these110 (71.42%) were of females and 44 (28.57%) were of males. Culture positive cases in the age group 21-40 years (52.59%) were the highest. Escherichia coli (29.22%) was the most common organism isolated followed by Klebsiella sps (18.18%) among gram negative bacilli and Staphylococcus aureus (10.38%) among gram positive cocci. Escherichia coli was 100% sensitive to nitrofurantoin, amikacin and imipenem. The isolation of Extended Spectrum Beta Lactamase (ESBL) among gram negative bacterial isolates was 2.5%. Staphylococcus aureus was sensitive to vancomycin and linezolid (100%)and all the isolates were Methicillin Sensitive Staphylococcus aureus (MSSA) Conclusion: UTI is most common in females and E.coli was the most common uropathogen isolated. Culture results and antibiogram help in the specific treatment and judicious antibiotic usage to prevent drug resistance.