{"title":"Discuss The Use Of Oncolytic Viruses As Cancer Therapeutics","authors":"Rachita Radhakrishna Pai","doi":"10.24966/cbcm-1943/100016","DOIUrl":null,"url":null,"abstract":"Cell death by oncolytic viruses occurs through direct or indirect mechanisms such as amplification of anti-cancer immune response, tumor blood vessels destruction or through transgene-encoded proteins manifested from modified viruses. Despite the different mode of action, the ultimate function of the oncolytic viruses is to disrupt the cancer cells’ transcriptional or","PeriodicalId":197884,"journal":{"name":"Cell Biology and Cell Metabolism","volume":"21 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell Biology and Cell Metabolism","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24966/cbcm-1943/100016","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Cell death by oncolytic viruses occurs through direct or indirect mechanisms such as amplification of anti-cancer immune response, tumor blood vessels destruction or through transgene-encoded proteins manifested from modified viruses. Despite the different mode of action, the ultimate function of the oncolytic viruses is to disrupt the cancer cells’ transcriptional or
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