Ultra Giant Vesicles out of a Planar Membrane

K. Funakoshi, H. Suzuki, S. Takeuchi
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Abstract

We report a method for forming ultra giant lipid vesicles. A chip device with a micro-jet nozzle was fabricated. The vesicles were produced by applying pulsed micro jets to a planar lipid bilayer, analogous to blowing soap bubbles from a liquid film. Using this method, lipid vesicles with diameters of about 500 mum were formed one-by-one. This method enables the encapsulation of target molecules or nano particles into the vesicles rapidly and efficiently
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平面膜外的超大囊泡
我们报告了一种形成超大脂质囊泡的方法。制作了一种带有微喷嘴的芯片装置。通过将脉冲微射流应用于平面脂质双分子层产生囊泡,类似于从液体膜中吹出肥皂泡。用这种方法,一个个形成直径约500 μ m的脂质囊泡。该方法能够快速有效地将目标分子或纳米颗粒封装到囊泡中
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