Analysis of the heart rate variability and stratification of the risk of cardiac patients with Chagas’ disease

Abstract

According to the World wide Organization of the Health, the number of people infected with the Tri-panosoma Cruzi is considered between 16 and 18 million, causal agent of the Chagaspsila disease, and in 100 million the people exposed to the affectation risk. When concluding in 1983 a study longitudinal epidemiologist in patients with the disease evaluated every 3 years, the cardiac affectation: chronic Chagasic myocarditis (MCHC) increased from a 17% at the beginning of the study to a 49, 4% after 15 years. Previous studies of the variability of cardiac frequency in patients with the Chagaspsila disease, show alterations in the spectral indices of the HRV. We analyze the 24-hour heart rate by Holter recordings in 62 patients with ECG alterations (CH2), 32 patients without ECG alterations (CH1) who had positive serological findings for disease of Chagaspsila and 36 healthy subjects (control) matched for sex and age. We find a orthogonal base that is able to discriminate the groups from circadian profiles, control and CH2, and stratify the groups CH1.