Survey on Feasibility of Pattern Matching Techniques In Heterogeneous Architectures for Bioinformatics

Ciprian-Petrisor Pungila, Darius Galis, V. Negru
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Abstract

Pattern-matching techniques are very common in major areas of bioinformatics, in multiple forms: from exact (accurate) to partial matching, the process itself is vital to multiple niches of research. In this paper, we prepare a survey of recent breakthroughs in the field of pattern-matching applied to bioinformatics, from a heterogeneous implementation standpoint, focusing especially on the ones based on SIMD (Single Instruction Multiple Data) or GPGPU (General-Purpose computing on Graphics Processing Units) architectures. We focus on the most important aspects of such data processing and their effectiveness, with particular focus on the technological challenges that such heterogeneous implementations bring, while also analyzing their feasibility of application to particular research niches, such as DNA analysis and protein sequence alignment.
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生物信息学异构架构中模式匹配技术的可行性调查
模式匹配技术在生物信息学的主要领域非常常见,有多种形式:从精确(准确)匹配到部分匹配,这一过程本身对多个研究领域至关重要。在本文中,我们从异构实现的角度出发,对应用于生物信息学的模式匹配领域的最新突破进行了调查,尤其侧重于基于 SIMD(单指令多数据)或 GPGPU(图形处理单元上的通用计算)架构的模式匹配。我们将重点放在此类数据处理的最重要方面及其有效性上,尤其关注此类异构实现所带来的技术挑战,同时分析它们应用于特定研究领域(如 DNA 分析和蛋白质序列比对)的可行性。
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