Cariprazina como alternativa farmacológica en el tratamiento de la psicosis en la enfermedad de Parkinson

Abstract

Introduction

Parkinson's disease (PD) frequently presents as a complication with the presence of psychotic symptoms.

Objective

To describe the therapeutic process of PD-related psychotic symptoms, evaluating possible pharmacological alternatives.

Clinical case

A 41-year-old woman with early diagnosis of PD (diagnosed at an early age), poor response to dopaminergic treatment, with the presence of psychotic symptoms and the need for a deep brain stimulator. The patient was admitted due to new onset of psychotic symptoms while on low-dose levodopa.

Result

After poor response to treatment with clozapine, cariprazine was tried with improvement of symptoms, good tolerability, and no side effects.

Conclusions

Cariprazine may be an alternative in the event of clozapine treatment failure.