Potential of Hepatoprotective Activity of Abelmoschus Moschatus Seed: In-Silico Validation

Abstract

A type of wound healing known as hepatic fibrosis arises in response to chronic liver damage brought on by viruses, toxins, and medications that are detrimental to the liver. The syndrome is characterized by inflammation, which is followed by the deposition of extracellular matrix proteins and the development of scar tissue. Ephrin receptor A2 is a host cofactor that has been associated to Hepatitis C virus (HCV) entry (EphA2). The Abelmoschus moschatus seed belong to family Malvaceae. It contains sitosterol b. total phenol, flavonoids which are responsible for antioxidant, antimicrobial and free radical scavenging activity. The exact mechanism of action for the hepatoprotective action of Myricetin was still not revealed. With intent to propose the most probable mechanism of action of Myricetin the docking based computational analysis has been performed against the hepatoprotective drug targets like PPARα enzyme. Research Article