Silver Diamine Fluoride: A Review

Obehi O Osadolor, A. Osadolor
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Abstract

BACKGROUND The burden of untreated dental caries among African children is high. Silver diamine fluoride (SDF) is a simple, non- technique sensitive intervention to stop the progression of active untreated carious lesion in primary teeth among children. Silver diamine fluoride (SDF) 38% solution contains 44,800 ppm fluoride ions and its stains teeth after use. METHOD An electronic literature search in Web of science, Scopus, PubMed, Google Scholar, African journal online, Researchgate and Google was done in May,2023. Search terms and keywords were combined by Boolean operators. Two independent investigators (research assistants) screened titles, abstracts and full text of publications. The inclusion criteria were original research articles, case report, case series related to silver diamine fluoride ( human studies) conducted in African region and in electronic databases. RESULTS Ten articles were included as they were assessed to meet the aim of the review. The study design of the articles were four invitro studies, three randomized controlled clinical trial, one randomized clinical trial, one split-mouth, self-controlled clinical trial and one split-mouth, randomized controlled clinical study. 90 % of the studies identified was conducted in Egypt, while 10 % of the studies was conducted in Nigeria. CONCLUSION Studies on silver diamine fluoride (SDF) identified in African countries were few and restricted to few countries. Silver diamine fluoride can be used as an intervention for active and progressing untreated carious lesion in primary teeth among children though it stains teeth after use. More studies from the diverse ethnic population in Africa will contribute to the existing literature.
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二胺氟化银:综述
背景:在非洲儿童中,未经治疗的龋齿负担很高。二胺氟化银(SDF)是一种简单、无技术敏感性的干预措施,可阻止儿童乳牙未治疗的活动性龋齿病变的发展。二胺氟化银(SDF) 38%溶液含44,800 ppm氟离子,使用后会染色牙齿。方法于2023年5月在Web of science、Scopus、PubMed、Google Scholar、African journal online、Researchgate和Google进行电子文献检索。搜索词和关键字由布尔运算符组合。两名独立调查人员(研究助理)筛选出版物的标题、摘要和全文。纳入标准是在非洲区域和电子数据库中进行的与氟化二胺银(人体研究)有关的原始研究文章、病例报告、病例系列。结果:10篇文章被纳入,因为它们被评估达到了综述的目的。文章的研究设计为4项体外研究、3项随机对照临床试验、1项随机对照临床试验、1项裂口自对照临床试验和1项裂口随机对照临床研究。所确定的研究中有90%是在埃及进行的,而10%是在尼日利亚进行的。结论非洲国家对氟化二胺银的研究较少,且仅限于少数国家。氟化二胺银可用于干预儿童乳牙活动性和进展性未经治疗的龋齿,但使用后会污染牙齿。更多来自非洲不同种族人口的研究将有助于现有文献。
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