Raphael Chinweike Okolo, S. A. Ufelle, Alphonsus Ogbonna Ogbuabor, Peter U. Achukwu
{"title":"A Messenger Ribonucleic Acid: A Platform for Protein Synthesis","authors":"Raphael Chinweike Okolo, S. A. Ufelle, Alphonsus Ogbonna Ogbuabor, Peter U. Achukwu","doi":"10.15226/sojmid/7/2/001102","DOIUrl":null,"url":null,"abstract":"The messenger Ribonucleic Acid (mRNA) has come to play as potential regulators of gene expression that is translates in the ribosome by the RNA polymerase and yields amino acid and protein. This plays a tremendous role in the protein synthesis and is not just mere template in translation but also contains essential regulatory elements as protein supplement, for therapy vaccine production and generation of pluripotent stem cells. This review highlights the new approaches and insights in the role of mRNA as a template in protein synthesis, functional approach, clinical uses and in vivo usage which is still a challenge underway. Keywords: MRNA; Translation; Protein synthesis; DNA; Gene regulation.","PeriodicalId":200618,"journal":{"name":"SOJ Microbiology & Infectious Diseases","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"SOJ Microbiology & Infectious Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15226/sojmid/7/2/001102","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The messenger Ribonucleic Acid (mRNA) has come to play as potential regulators of gene expression that is translates in the ribosome by the RNA polymerase and yields amino acid and protein. This plays a tremendous role in the protein synthesis and is not just mere template in translation but also contains essential regulatory elements as protein supplement, for therapy vaccine production and generation of pluripotent stem cells. This review highlights the new approaches and insights in the role of mRNA as a template in protein synthesis, functional approach, clinical uses and in vivo usage which is still a challenge underway. Keywords: MRNA; Translation; Protein synthesis; DNA; Gene regulation.
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