FACTORS AFFECTING THE FUNCTIONAL STATUS OF PATIENT WITH MENINGIOMA IN DR. SAIFUL ANWAR GENERAL HOSPITAL MALANG

Dessika Rahmawati, B. Munir, N. Setijowati, Catur Ari Setianto, Ria Damayanti, Bimo Mubyarto
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Abstract

Background: Meningioma is one of the most commonly reported primary central nervous system (CNS) tumors, originating from arachnoid meningeal cells and including intracranial extra-axial neoplasms. Although meningioma is considerably benign, the patient conditions are reported to be diverse resulting in severe and life-threatening neurological deficits. Hence the assessment regarding functional status is deemed pivotal to provide a prognostic perspective as patient presentation exhibits disability due to lesions and other factors. Objective: This research aims to analyze factors affecting the functional status of patients with meningioma in Dr. Saiful Anwar General Hospital Malang. Methods: An analytic retrospective study was conducted with cross-sectional study involving 62 samples from patients visits with meningioma brain tumor in RSUD dr. Saiful Anwar General Hospital Malang from January 2017 to December 2020. The data was selected through non-probability sampling, generating sampling type from brain tumor register data Neurology. Results: Data obtained from 62 meningioma patients in RSUD dr. Saiful Anwar General Hospital Malang met the inclusion criteria from January 2017 to December 2020, based on demographic characteristics such as age of <50 in 38 patients (61.3%) and age of >50 in 24 patients (38.7%). Clinically, it was found that 58 patients (93.5%) experienced headache, 28 patients (45.2%) experienced decreasing consciousness, 15 patients (24.2%) had hemiplegia, and 17 patients (27.4%) had hemiparesis, 17 people had hemiparesis. 17 patients (27.4%) experienced visual disturbances, and 24 patients (38.7%) are with seizures. Based on the radiology screening sites, 46 patients (74.2%) were screened in Convexity sphere, 9 patients (14.5%) were screened at Cranial base, 3 patients (4.8%) were screened at Parasagittal, and 4 patients (6.5%) were screene at Falx, from which the 41 patients (66.1%) exhibited herniation. Based on comorbidities, 12 patients (19.4%) had sepsis, and 1 patient (1.6%) had pneumonia. From the analysis test results, it was found that decreasing consciousness (GCS) was significantly correlated with functional status, referred to Karnofsky Performance Scale of <70 (p: 0.013, p <0.05). Seizures were reported to be correlated significantly with functional status, referred to Karnofsky Performance Scale of > 70 (p: 0.015, p<0.05). Tumor location was significantly correlated with functional status, reffered to Karnofsky Performance Scale of > 70 (p: 0.027, p<0.05). Conclusion: The factors affecting the functional status based on the Karnofsky Performance Scale (KPS) of a patient with meningioma at Dr. Saiful Anwar General Hospital Malang included: decreasing consciousness (GCS), and seizures, and tumor location.
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马朗安华医生总医院脑膜瘤患者功能状态的影响因素
背景:脑膜瘤是最常见的原发性中枢神经系统(CNS)肿瘤之一,起源于蛛网膜脑膜细胞,包括颅内轴外肿瘤。虽然脑膜瘤是相当良性的,但据报道,患者的病情多种多样,导致严重和危及生命的神经功能障碍。因此,当患者表现出因病变和其他因素导致的残疾时,对功能状态的评估被认为是提供预后观点的关键。目的:分析马琅赛弗·安华总医院脑膜瘤患者功能状态的影响因素。方法:采用横断面研究方法,对2017年1月至2020年12月在马朗赛弗·安华总医院就诊的脑膜瘤脑肿瘤患者62例样本进行回顾性分析。数据采用非概率抽样,从脑肿瘤登记数据中生成抽样类型。结果:2017年1月至2020年12月,根据24例患者(38.7%)的年龄为50岁等人口统计学特征,来自马朗赛弗·安瓦尔总医院的62例RSUD脑膜瘤患者的数据符合纳入标准。临床发现头痛58例(93.5%),意识减退28例(45.2%),偏瘫15例(24.2%),偏瘫17例(27.4%),偏瘫17例(27.4%)。17例患者(27.4%)出现视力障碍,24例患者(38.7%)出现癫痫发作。从影像学筛查部位来看,凸球区筛查46例(74.2%),颅底区筛查9例(14.5%),矢旁区筛查3例(4.8%),Falx区筛查4例(6.5%),其中41例(66.1%)表现为疝。根据合并症,12例(19.4%)患者有脓毒症,1例(1.6%)患者有肺炎。从分析检验结果来看,意识下降(GCS)与功能状态显著相关,参照Karnofsky绩效量表70 (p: 0.015, p: 0.027, p<0.05)。结论:马朗赛弗·安瓦尔总医院1例脑膜瘤患者的Karnofsky功能量表(KPS)显示影响脑膜瘤功能状态的因素包括:意识下降(GCS)、癫痫发作和肿瘤位置。
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