[Changes in hemoglobin in patients with hemolytic anemia].

Archivos de investigacion medica Pub Date : 1990-10-01
G Pérez, M E de la Peña, A Esparza, A Mejía, V Vázquez, J C Aguilar Luna, J González, B López-Guido, M L Ornelas, B Ibarra
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Abstract

Hb alterations studied throughout 2 years in 129 patients are reported, these patients had hemolytic anemia or the possibility of a hemoglobinopathy : 5 were heterozygotes to thalassemia b; 3 were compound-heterozygote of thalassemia a1 and thalassemia a2; 2 for thalassemia b and 2 for thalassemia b and Hb S; 2 homozygotes and 2 heterozygotes for Hb S; 2 was bearing unstable Hb and the other had Hereditary Persistence of Hb F. These results allow the conclusion that thalassemia is the Hb alteration which most frequently causes hemolytic anemia in our population and underscores the importance of the study of these pathologies in selected populations.

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溶血性贫血患者血红蛋白的变化。
研究了129例患者2年来的Hb改变,这些患者患有溶血性贫血或可能患有血红蛋白病:5例是地中海贫血b的杂合子;3例为地中海贫血a1和地中海贫血a2的复合杂合子;2例地中海贫血b和2例地中海贫血b和Hb S;Hb S有2个纯合子和2个杂合子;2例携带不稳定Hb,另1例携带Hb f遗传持续性。这些结果表明,地中海贫血是在我们的人群中最常引起溶血性贫血的Hb改变,并强调了在选定人群中研究这些病理的重要性。
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