Early Detection of Parkinson's Disease using Spiral Test and Echo State Networks

Lerina Aversano, M. Bernardi, Marta Cimitile, Martina Iammarino, Chiara Verdone
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引用次数: 3

Abstract

Parkinson's disease is one of the most prevalent neurodegenerative diseases in the world, usually occurring after the age of 50, but in some cases, also affects younger people. It is a disease that affects movement, coordination, and muscle control, all of which cause a range of symptoms that affect patients' writing and drawing skills. Diagnosis is clinical, so it occurs mainly through the evaluation of the patient's movements, coordination, and muscle control. Therefore, the analysis of micrographic models can introduce a new methodology of investigation in the diagnosis and monitoring of Parkinson's disease. This study proposes an approach based on artificial intelligence in combination with the spiral test, which consists in asking the patient to draw a spiral, thanks to which it is possible to make the early diagnosis of Parkinson's disease. The classification is performed with a combination of an Echo State Network and an MLP layer. To validate the approach, several classification algorithms belonging to two macro groups (boosting decision trees based) were used as baseline. The results obtained are very satisfactory with the ESN-based classifier exhibiting an F-Score of 97.8%. The very encouraging results indicate that the proposed approach may be an effective contribution to improving Parkinson's diagnostics.
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利用螺旋试验和回声状态网络早期检测帕金森病
帕金森氏症是世界上最常见的神经退行性疾病之一,通常发生在50岁以后,但在某些情况下,也会影响年轻人。这是一种影响运动、协调和肌肉控制的疾病,所有这些都会导致一系列症状,影响患者的写作和绘画技能。诊断是临床的,因此主要是通过对患者的运动、协调和肌肉控制的评估来进行的。因此,显微模型的分析可以为帕金森病的诊断和监测提供一种新的研究方法。该研究提出了一种基于人工智能的方法,该方法与螺旋测试相结合,即让患者画螺旋,从而可以早期诊断帕金森病。分类是通过回声状态网络和MLP层的组合来完成的。为了验证该方法,使用了属于两个宏观组(基于增强决策树)的几种分类算法作为基线。结果非常令人满意,基于esn的分类器的F-Score为97.8%。令人鼓舞的结果表明,所提出的方法可能是改善帕金森病诊断的有效贡献。
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