Gender Predliction and Confunding Factors Affecting Pre Hospital Delay Among Acute Myocardial Infraction Patients.

Jayesh Sharma, Avanish Bhardwaj
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Abstract

Background: Acute Myocardial Infarction (AMI) is a serious and life-threatening manifestation of coronary artery disease (CAD) affecting both males and females, which need immediate management. The present study was aimed to assess the gender difference and factors affecting pre-hospital delay among patients with AMI.Subjects and Methods:The 291 patients admitted with AMI from01-01-2018 to 31-12-2018 were studied. A descriptive comparative design was adopted for the study. Socio personal and clinical variables of the subjects were assessed. Pre-hospital delay was measured in terms of time from the onset of symptoms till the patient reaches a health care setting. One hour after the onset of symptom of AMI was considered as the Golden hour. Data was analyzed using SPSS 20.0 software.Results:Out of the 291 patients with AMI (146 males and 145 females), only 32.4% of males and 24.1% of females reached a health care setting within 1 hr of onset of symptoms. 35.2% of male patients and 43.5% of female patients reached the health care setting only after 6 hrs of onset of symptoms. Among the male patients, pre hospital delay was significantly associated with place of onset of symptoms (p<0.05), presence of someone with the patient at the time of onset of symptoms (p<0.05), and perception of symptoms developed, as an emergency (P<0.001). Whereas in female patients, significant association was observed in pre hospital delay with age of the patient (p<0.05), nature of the first symptom experienced (P<0.05) and perception of symptoms developed as an emergency (p<0.001).Conclusion: Our study shows the existence of pre hospital delay among patients with AMI in both males and females. The factors affecting pre hospital delay vary between males & females.
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急性心肌梗死患者院前延迟的性别预测及混杂因素
背景:急性心肌梗死(AMI)是冠状动脉疾病(CAD)的一种严重且危及生命的表现,男女均可发生,需要立即治疗。本研究旨在探讨AMI患者院前延迟的性别差异及影响因素。对象与方法:对2018年01月1日至2018年12月31日住院的291例AMI患者进行研究。本研究采用描述性比较设计。评估受试者的社会、个人和临床变量。院前延迟是根据从症状出现到患者到达卫生保健机构的时间来衡量的。AMI症状出现后1小时为黄金时间。数据分析采用SPSS 20.0软件。结果:291例AMI患者(男性146例,女性145例)中,只有32.4%的男性和24.1%的女性在症状出现后1小时内到达医疗机构。35.2%的男性患者和43.5%的女性患者在症状出现6小时后才到达卫生保健机构。在男性患者中,院前延迟与症状发生地点(p<0.05)、症状发生时有人陪同(p<0.05)以及症状发展为紧急情况的感知(p< 0.001)显著相关。而在女性患者中,院前延迟与患者的年龄(p<0.05)、首次症状的性质(p<0.05)和对症状发展为紧急情况的感知(p<0.001)显著相关。结论:我们的研究显示AMI患者院前延迟在男性和女性中都存在。影响院前延误的因素在男性和女性之间存在差异。
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