[New organ-preserving technics for third-grade splenic trauma. An experimental study].

S Uranüs, L Kronberger, A Beham, K Neumayer, W Kröll, D Aktuna
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Abstract

We studied two new techniques for orthotopic preservation of the spleen in an animal model with respect to their technical feasibility and their hemostatic efficacy. This study was performed in two stages. In the first, the treatment of central bursting ruptures by splenorrhaphy using a resorbable compressive mesh was tested. 20 sheep have been used for this part of the study. They were divided into four groups (A: control, B: sham operation, C: splenectomy, D: mesh splenorrhaphy). Following completion of this stage, two animals from group A and two from group B were used to test a second experimental setting. Experimental trauma corresponding to isolated third degree polar rupture of the spleen was induced. This was then treated by a polar resection using stapling instruments. All animals from each stage were subjected to spleen scanning three months postoperatively, followed by splenectomy. The spleens were then examined histologically. Both macroscopically and microscopically normal splenic tissue was found. No difference between the different groups could be detected by laboratory investigations. Gamma-globulins and total serum proteins were within normal ranges after five weeks. Splenic scan revealed an excellent function of the pulp. Both techniques are distinguished by their facility and rapidity, as well as reliable hemostasis and minimal technical prerequisites.

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三级脾损伤保器官新技术。一项实验研究]。
我们在动物模型上研究了两种原位保存脾脏的新技术的技术可行性和止血效果。本研究分两个阶段进行。首先,通过使用可吸收压缩网进行脾脏修补治疗中央破裂进行了测试。这部分研究使用了20只羊。患者分为4组(A:对照组、B:假手术组、C:脾切除术组、D:网状脾切除术组)。在这一阶段完成后,A组和B组的两只动物被用于第二个实验环境的测试。实验创伤对应于离体脾三度极性破裂。然后用吻合器进行极性切除治疗。每个阶段的所有动物术后3个月进行脾脏扫描,然后进行脾切除术。然后对脾脏进行组织学检查。肉眼和显微镜下均见脾脏组织正常。实验室调查未发现不同组之间的差异。5周后γ -球蛋白和血清总蛋白均在正常范围内。脾扫描显示牙髓功能良好。这两种技术的特点是它们的便利和快速,以及可靠的止血和最低的技术要求。
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