Hemoglobin A2 and F in patients with psoriasis.

Dermatologische Monatschrift Pub Date : 1990-01-01
N Zlatkov, L Damianova, K Prodanov, N Kiriakova
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Abstract

HbA2 and HbF were studied in 91 patients with different forms of psoriasis: 29 with psoriasis vulgaris placata (restricted forms); 31 with psoriasis generalisata and erythroderma psoriaticum; 21 with psoriatic arthritis; 10 with psoriasis pustulosa. Statistically significant increase of HbA2 was established in patients with psoriasis vulgaris placata (restricted forms) as well in patients with psoriatic arthritis. HbF is statistically significant increased in all forms of psoriasis. The authors suggest, that there is probably in psoriasis a disturbance in the synthesis of the globine chains, which is genetically dependent.

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银屑病患者血红蛋白A2和F的变化。
研究了91例不同类型银屑病患者的HbA2和HbF: 29例寻常型银屑病(限制型);全身性银屑病和银屑病红皮病31例;银屑病关节炎21例;10伴有牛皮癣脓疱。寻常型银屑病(限制型)和银屑病关节炎患者的HbA2水平均有统计学意义的升高。HbF在所有形式的牛皮癣中都有统计学意义的增加。作者认为,银屑病中可能存在球蛋白链合成紊乱,这是遗传依赖性的。
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