Severe course of diabetic ketoacidosis due to new coronavirus infection in older children (clinical cases)

L. Ditkovskaya, Y. Aleksandrovich, K. V. Pshenisnov, Yu. A. Demchuk, E. Y. Fel’ker
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Abstract

   The risk of severe type I diabetes mellitus in children with new coronavirus infection (COVID-19) is extremely high, which is associated with a high risk of intracranial hypertension, cerebral edema and multiple organ dysfunction syndrome. On the example of a clinical case, the features of the course of diabetic ketoacidosis and intensive care measures in children with COVID-19 were considered. The main data of the history and clinical and laboratory examination are reflected, special attention is paid to the applied aspects of therapy, it was noted that with a severe course of a new coronavirus infection and diabetic ketoacidosis, the risk of developing cerebral injury, acute kidney injury and thromboembolic complications is quite high, which may require artificial lung ventilation for the purpose of cerebral protection, renal replacement therapy and the use of anticoagulants. The new coronavirus infection is a risk factor for the severe course of diabetic ketoacidosis in children with type I diabetes, regardless of the age of the child, which is the basis for clinical alertness in order to timely identify and treat potential life-threatening complications.
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大龄儿童新型冠状病毒感染所致糖尿病酮症酸中毒重症病程(临床病例)
新型冠状病毒感染(COVID-19)患儿发生严重I型糖尿病的风险极高,并伴有颅内高压、脑水肿和多器官功能障碍综合征的高风险。结合1例临床病例,探讨新冠肺炎患儿糖尿病酮症酸中毒病程特点及重症监护措施。反映了病史、临床及实验室检查的主要资料,特别关注治疗的应用方面,指出重症新型冠状病毒感染合并糖尿病酮症酸中毒,发生脑损伤、急性肾损伤及血栓栓塞并发症的风险相当高,可能需要人工肺通气进行脑保护、肾脏替代治疗和使用抗凝剂。新型冠状病毒感染是1型糖尿病儿童发生严重糖尿病酮症酸中毒病程的危险因素,无论儿童年龄如何,这是临床提高警觉性的依据,以便及时发现和治疗潜在的危及生命的并发症。
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