ReadiGraft BLX Putty and ReadiGraft Bone Chips in the Treatment of Severe Osteoarthropathy in Hemodialysed Patient.

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Abstract

Abstract Osteoarticular complications are a major concern in patients treated with long-term hemodialysis, hemofiltration or continuous ambulatory peritoneal dialysis. Uremic chronic patients, treated for long periods of time (≥15 years) with hemodialysis, could develop a new kind of osteoarthropathy due to amyloidosis characterized by abnormal distribution of beta-2 microglobulin (B2M) in joint tissue. Deposits of B2M are responsible for several lesions, clinically evident in different pathologies, such as: carpal tunnel syndrome, spondylarthrosis, and hemodialysis osteoarthropathy.
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ReadiGraft BLX油灰与ReadiGraft骨芯片治疗血液透析患者重症骨关节病的疗效观察。
骨关节并发症是长期血液透析、血液滤过或连续动态腹膜透析患者的主要关注点。尿毒症慢性患者长期(≥15年)进行血液透析治疗,可发展为一种以关节组织β -2微球蛋白(B2M)分布异常为特征的淀粉样变骨关节病。B2M的沉积可导致多种病变,临床表现为不同的病理,如:腕管综合征、脊柱关节病和血液透析骨关节病。
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