Is Prolonged Sitting a Risk Factor in Developing Hemorrhoids and Anal Fissures?

Gamal E.H.A. Shallaly, Elfatih M Malik, Mohamed Abdelmonem Ali, Maysa H. M. Hamza, Babikir A. B. Ibrahim, Hassan E.H.M. Ahmed, Mohamed M. I. Elhajahmed, Modather M.E. Salih
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Abstract

Background: Anal fissures and hemorrhoids are common anal conditions. They cause significant morbidity, social embarrassment, and work absenteeism. In addition, they form a significant workload on the healthcare system. Nevertheless, the etiology of these conditions is still contentious. It has been observed that hemorrhoids and anal fissures are associated with prolonged sitting. This study aims to investigate this observation.Methods: This is a case–control study. We compared 81 patients with symptomatic and endoscopically proven hemorrhoids and/or anal fissures with 162 controls with no symptoms or endoscopic evidence of perianal disease. The study was conducted at Khartoum North Teaching Hospital (KNTH) endoscopy unit between January and December 2019. Demographic data, sitting hours per day, and endoscopic findings of patients and controls were recorded in a proforma. The cases and controls were matched for age, sex, and bowel habits. Data were analyzed and compared using the SPSS version 23.Results: The mean sitting hours for cases was 5.99 (SD 3.4) whereas that for controls was 4.0 (SD 3.0) with a highly significant difference (P < 0.001). Sitting for 5 hr or more per day (exposure) was associated with an increased risk of developing hemorrhoids and/or anal fissures [odds ratio 3.68, 95% CI: 2.1–6.47].Conclusion: The study showed that sitting down for 5 hr or more per day might increase the risk of developing hemorrhoids and/or anal fissures. This finding could help in the prevention and treatment of these diseases and the reduction of recurrences.
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久坐是患痔疮和肛裂的危险因素吗?
背景:肛裂和痔疮是常见的肛门疾病。它们会导致严重的发病率、社交尴尬和旷工。此外,他们对医疗保健系统构成了巨大的工作量。然而,这些疾病的病因仍有争议。据观察,痔疮和肛裂与久坐有关。本研究旨在调查这一观察结果。方法:采用病例-对照研究。我们比较了81例经内窥镜证实有症状的痔疮和/或肛裂患者和162例没有症状或内窥镜证实有肛周疾病的对照组。该研究于2019年1月至12月在喀土穆北部教学医院(KNTH)内窥镜检查部门进行。以形式记录了患者和对照组的人口统计数据、每天坐着的时间以及内窥镜检查结果。这些病例和对照组在年龄、性别和排便习惯上都是匹配的。数据分析比较采用SPSS version 23。结果:两组患者平均坐下时间为5.99小时(SD 3.4),对照组平均坐下时间为4.0小时(SD 3.0),差异有显著性意义(P < 0.001)。每天坐5小时或更长时间(暴露)与患痔疮和/或肛裂的风险增加相关[优势比3.68,95% CI: 2.1-6.47]。结论:研究表明,每天坐5小时或更长时间可能会增加患痔疮和/或肛裂的风险。这一发现有助于预防和治疗这些疾病,并减少复发率。
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