{"title":"Various signal molecules modulate voltage-activated ion currents on snail neurons.","authors":"A Szücs, G B Stefano, T K Hughes, K S Rózsa","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The modulatory effects of interleukin-1 (IL-1), an immunotransmitter, and FMRFamide, a molluscan neuropeptide, were studied on identified neurons of Helix pomatia L. (Mollusca, Gastropoda) by using the method of two microelectrode voltage clamp. IL-1 and FMRFamide uniformly decreased the voltage-activated inward current (ICa), while the voltage-dependent outward potassium current (Inet K) increased. IL-1 and FMRFamide were shown to use the same cellular targets as used by the low molecular weight neurotransmitters.</p>","PeriodicalId":77479,"journal":{"name":"Acta biochimica et biophysica Hungarica","volume":"26 1-4","pages":"139-43"},"PeriodicalIF":0.0000,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta biochimica et biophysica Hungarica","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The modulatory effects of interleukin-1 (IL-1), an immunotransmitter, and FMRFamide, a molluscan neuropeptide, were studied on identified neurons of Helix pomatia L. (Mollusca, Gastropoda) by using the method of two microelectrode voltage clamp. IL-1 and FMRFamide uniformly decreased the voltage-activated inward current (ICa), while the voltage-dependent outward potassium current (Inet K) increased. IL-1 and FMRFamide were shown to use the same cellular targets as used by the low molecular weight neurotransmitters.
分享
京公网安备 11010802042870号
京ICP备2023020795号-1
求助内容：
应助结果提醒方式：
扫码关注我们
