Evaluation of Various Treatment Modalities in Treating Diarrhoea Patient’s at a Tertiary Care Centre: A Comparative Analysis

Abstract

Background: Diarrhea is a common problem affecting up to 5% of the population at a given time. Patients vary in their definition of diarrhea, citing loose stool consistency, increased frequency, urgency of bowel movements, or incontinence as key symptoms. The present study was conducted to evaluate and compare various treatment modalities in treating diarrhoea patients at a tertiary care centre. Subjects and Methods: The present study was conducted to evaluate and compare various treatment modalities in treating 240 diarrhoea patients. All the patients were grouped into three study groups with 80 patients in each group: group 1- included patients who were given Metronidazole therapy, group 2- patients who were given Ofloxacin therapy, and group 3 – patients who were given Norfloxacin therapy. Stool samples were obtained from patients of all the study groups for assessing the effectiveness of treatment therapy. Only clinical success was recorded. Statistical analysis was performed using the Statistical Package for the Social Sciences software version 21.0 (SPSS Inc., Chicago, IL, USA) and level of significance was assessed using Chi- square test. Results: In our study total sample size was 240 in which 175 were males and 65 were females. In group 1 patients with 3 to 4 times stool per day were 29 and more than 4 times per day were 53 whereas in group 2 patients with 3 to 4 times stool per day were 34 and more than 4 times per day were 49 and in group 3 patients with 3 to 4 times stool per day was 31 and more than 4 times per day were 44. The clinical success of group 1 was 96% , group 2 was 93.97% and group 3 was 93.33%. Conclusion: Present study concluded that Metronidazole therapy had better clinical success than Ofloxacin therapy and Norfloxacin therapy.